Healthy Turkey Tetrazzini (2024)

This Healthy Turkey Tetrazzini recipe (with cream of mushroom soup) is old fashioned comfort food that's easy to make and great for using up leftover spaghetti noodles and/or leftover turkey!

This healthy Turkey Tetrazzini is most popular during the colder months and when you have leftover Thanksgiving turkey. This recipe was inspired by my Easy Turkey Pot Pie (with cream of chicken soup) on this site, and pairs well with Italian Breadsticks.

🥘Ingredients

For this turkey casserole, you don't need heavy cream or cream cheese to get a creamy sauce. Made with simple ingredients like chunks of turkey, spaghetti noodles, and frozen mixed vegetables, you'll find you have most (if not all) the ingredients on hand. For this healthier version, you'll need the following ingredients:

• Mushrooms: Using fresh mushrooms is critical to this recipe, as well as cooking them with the butter and onion
• 10 oz can of condensed cream of mushroom soup *see TOP TIP
• Milk- I use 1%

🔪Instructions

Prep: Preheat oven to 375°F (190 degrees C). If you are not using leftover spaghetti noodles, cook spaghetti according to package directions (al dente) and drain. Cook turkey and chop into bite-sized pieces (if not using cooked leftover turkey). Spray a 3 quart casserole dish with non-stick cooking spray.

Mix mushrooms, onions, butter and salt together in a medium bowl.

Cook for 5 minutes in microwave.

Transfer spaghetti noodles, mushrooms, butter and onion to a large bowl and stir in remainder of ingredients (except mozzarella cheese)

Transfer into prepared casserole dish

Add grated mozzarella cheese.

Bake, uncovered, until heated through, 30-35 minutes until mushrooms and onions are cooked.

Turn up to 500 degrees F/260 degrees C (broil) for 2 minutes until cheese is bubbly and lightly browned. Keep a close eye on it so it doesn't burn.

If desired, sprinkle with fresh parsley.

📖Variations & Substitutions

• Noodles - you can use any type of noodles such as thin spaghetti (spaghettini) angel hair pasta, or fettucine. You could also use whole wheat spaghetti noodles or a lighter WW noodle (see WW points section)
• Turkey - you could use leftover turkey, turkey breast, ground turkey, chicken breast or rotisserie chicken.
• Cheese- you can use cheddar cheese or monterey jack cheese instead.
• Add-ins - you can add in bell pepper if you like.

🥗 Side Dishes

This turkey casserole pairs perfectly with a simple garlic toast. But here are a few of my favorite dishes to serve with turkey tetrazzini:

🍽Equipment

You will need a large bowl, a cutting board, a sharp knife, a 3 quart casserole dish,(affiliate link), a cheese grater and for this Tetrazzini casserole (see recipe card for equipment links and photos).
I highly recommend these silicone trivets from Thermoworks (affiliate link). They are the best trivets I've ever owned because they can withstand really high heat, are super durable and you can just pop them into the dishwasher!

🌡️Storage

Store leftover turkey tetrazzini in an airtight container in the fridge. If you are just storing a small amount or storing it overnight, you can cover it in plastic wrap. This recipe freezes well in a sealed container and can be frozen for up to 3 months.

👪 Serving Size

This easy turkey tetrazzini recipe makes 10 servings @ a little over a cup per serving. However, you can half, double or triple the recipe by clicking on theblueserving number and selecting the number of servings you'd like. The ingredient quantities will automatically adjust.

💭Top tip

If you have run out of condensed cream of mushroom soup, you can make your own! Just scroll down to #17 on this Kitchen hack post to find out how to make 'cream of anything soup'!

🦺Food safety

• Cook turkey breast to an internal minimum temperature of 165 °F (74 °C)
• Do not use the same utensils on cooked food, that previously touched raw meat
• Wash hands after touching raw meat
• Don't leave food sitting out at room temperature for extended periods
• Always have good ventilation when using a gas stove
• Never leave cooking food unattended

  See more guidelines at USDA.gov

❔ Frequently Asked Questions

If you're looking for a Turkey Tetrazzini recipe that's healthy, one that uses up leftover holiday turkey, is delicious and easy, then give this one a try!

FOR MORE LEFTOVER RECIPES click HERE!

🍲More Easy Casseroles